Individuals who are considering IVF at the best IVF centre in Bathinda as a way to conceive are often curious about preimplantation genetic testing (PGT). This efficient technique helps to assess the embryo to identify genetic disorders before implantation under the IVF treatment. For couples who are influenced by certain hereditary conditions or have experienced frequent miscarriages, PGT may prove to be a great option for them. Read on to get an insight into preimplantation genetic testing and the benefits the advanced technology science has to offer at the best IVF centre in Punjab.

What Is Preimplantation Genetic Testing?

Preimplantation genetic testing (PGT) is an advanced technological procedure that allows individuals to identify any genetic abnormalities in embryos before they are implanted in the lining of the uterine wall during an IVF cycle. The early identification of these abnormalities, PGT, helps individuals to only use healthy embryos for implantation, preventing any risk to the mother as well as the child. 

The PGT Process: Step-by-Step

The process of preimplantation genetic testing takes place with a standard IVF cycle: 

• Ovarian Stimulation And Egg Retrieval: Both ovaries in women are stimulated for the production of multiple eggs, which are retrieved through surgical methods.

• Fertilisation: After the retrieval, the eggs are fertilised in the lab until they develop into embryos. 

• Embryo Development: Embryos are maintained under a suitable environment for a few days until they reach a specific developmental stage, generally the stage of the blastocyst.

• Embryo Biopsy: From each embryo, a small number of cells are extracted. The procedure does not cause harm to the development of the embryo.

• Genetic Testing: Genetic testing is conducted on the extracted embryos in the lab to identify any specific genetic disorders.

• Embryo selection: Embryos that are healthy and free from any genetic conditions are selected for the implant depending upon the genetic testing result.

• Embryo Transfer: An embryo that is healthy is selected for transfer into the uterus, where it implants itself on the uterine lining to initiate development at the best IVF centre in Punjab.

Types Of Preimplantation Genetic Testing

PGT or Preimplantation Genetic Testing incorporates a number of types that are responsible for dealing with different genetic issues. The primary types of PGT are PGT-A, PGT-M, PGT-SR.

PGT-A (Preimplantation Genetic Testing For Aneuploidies)

PGT is performed to assess embryos for aneuploidies. These are deformities in the number of chromosomes. Conditions such as Down syndrome, turner syndrome, and Edwards syndrome can be caused by Aneuploidies. The detection of abnormalities through PGT-A allows the selection of embryos with an adequate number of chromosomes. This elevates the chances of successful conception and reduces the risk of miscarriage.

PGT-M ( Preimplantation Genetic Testing For Monogenic Disorders):

PGT-M is responsible for identifying a single specific gene disorder in embryos. These disorders are hereditary conditions influenced by mutations in a single gene.  Examples of the conditions include cystic fibrosis, sickle cell anaemia and Huntington's disease. PGT-M helps individuals reduce the risk of passing on these genetic disorders by selecting embryos that do not carry defective genes.

PGT-SR (Preimplantation Genetic Testing For Structural Rearrangements): 

This type of PGT is responsible for identifying the structural chromosome rearrangements, including translocations, inversions and deletions. The embryos can have imbalances in the chromosomes due to these rearrangements, which can result in miscarriages or congenital disabilities. PGT-SR enables couples seeking successful and healthy pregnancies to select embryos with balanced chromosomal structures and activate what they desire.

Why Choose PGT?

Preimplantation genetic testing at the best IVF centre in Ludhiana is opted for by individuals for several reasons, such as:

Reduced Risk Of Genetic Disorders

PGT helps to detect a number of genetic conditions, including Down syndrome, cystic fibrosis and BRCA mutations. The test helps to decrease the chances of passing on these genetic conditions to the offspring. 

Enhanced Chances Of Successful Pregnancy

Selecting only healthy embryos to be transferred into the uterus increases the chances of implantation, which leads to successful pregnancy at the best IVF centre in Punjab.

Planning For a Healthier Future

Couples can plan a healthy future for their offspring by ensuring that they are free from any known genetic conditions with the help of PGT. This gives them peace of mind and a sense of relaxation. 

Who Should Opt For PGT?

• Couples with a history of hereditary conditions.

• Individuals of advanced maternal age. 

• Individuals with recurrent miscarriages.

• People with a family history of chromosomal rearrangements.

• Individuals with unexplained issues of infertility.

• Couples are going through IVF after a number of failed attempts.

PGT is an ideal technique for those who represent a high risk of passing on genetic disorders to their offspring. The technique helps the intended parents to prevent their child from any abnormalities and ensure healthy growth in the future. 

This insight into PGT can help couples seeking a successful pregnancy to make wise decisions during their IVF cycle. They can consult the best IVF centre in Ludhiana to learn more about PGT and keep it in consideration as they choose assisted reproductive technology to achieve conception.